Autologous bone marrow stem cell transplantation for patients undergoing coronary artery bypass grafting: a meta-analysis of 22 randomized controlled trials.

ABSTRACT:

Background

Although the safety and feasibility of coronary artery bypass grafting (CABG) and bone marrow stem cell (BMSC) transplantation have been established, the effectiveness of this approach compared with CABG alone remains controversial. The aim of this updated meta-analysis of randomized controlled trials was to evaluate the efficacy of this procedure.

Methods

A random-effects meta-analysis was conducted using studies sourced from the PubMed, Embase, and Cochrane literature databases to compare patients who received isolated CABG (CABG group) and BMSC transplantation with CABG (BMSC group). 22 studies were included.

Results

A total of 22 relevant publications with 820 patients were included. 432 patients received BMSC transplantation with CABG and 388 patients

SUBMITTER: Song J 

PROVIDER: S-EPMC9233763 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature