Chemical composition, anticancer and antibacterial activity of Nepeta mahanensis essential oil.

ABSTRACT:

Background

Conventional cancer treatments, such as chemotherapy, radiation therapy, and surgery, often affect the patients' quality of life due to their serious side effects, indicating the urgent need to develop less toxic and more effective alternative treatments. Medicinal plants and their derivatives are invaluable sources for such remedies. The present study aimed to determine the chemical composition, anticancer and antibacterial activities of Nepeta mahanesis essential oil (EO).

Methods

The chemical composition of EO was analyzed by gas chromatography-mass spectrometry (GC-MS). Cytotoxicity and apoptosis/necrosis induction of EO was analyzed by MTT assay and Flow cytometry. Real-time PCR was performed to evaluate the Bax/Bcl2 gene expression. Also, the effect of the E

SUBMITTER: Amirzadeh M 

PROVIDER: S-EPMC9233784 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature