Sympathetic-mediated blunting of forearm vasodilation is similar between young men and women.

ABSTRACT:

Background

The in-vivo regulation of vascular conductance (VC) is a continuous balance between endothelial vasodilation and sympathetic vasoconstriction. Although women may report blunted sympathetic vasoconstriction along with higher endothelial vasodilation than men, it is currently unknown whether the interaction between vasoconstriction and vasodilation leads to different regulation of VC between sexes. This study assessed sex differences in sympathetic-mediated blunting of endothelial vasodilation after a brief period of ischemia and whether any restriction of vasodilation blunts tissue blood flow (BF) and re-oxygenation.

Methods

13 young women and 12 young men underwent two 5-min forearm circulatory occlusions followed by reperfusion, one in basal conditions and the ot

SUBMITTER: Gentilin A 

PROVIDER: S-EPMC9233837 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature