Interleukin (IL)-33 immunobiology in asthma and airway inflammatory diseases.

ABSTRACT:

Objective

Identify key features of IL-33 immunobiology important in allergic and nonallergic airway inflammatory diseases and potential therapeutic strategies to reduce disease burden.

Data sources

PubMed, clinicaltrials.gov.

Study selections

A systematic and focused literature search was conducted of PubMed from March 2021 to December 2021 using keywords to either PubMed or BioMed Explorer including IL-33/ST2, genetic polymorphisms, transcription, translation, post-translation modification, nuclear protein, allergy, asthma, and lung disease. Clinical trial information on IL-33 was extracted from clinicaltrials.gov in August 2021.

Results

In total, 72 publications with relevance to IL-33 immunobiology and/or clinical lung disease were identified (allergic airwa

SUBMITTER: Gaurav R 

PROVIDER: S-EPMC9234100 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature