Diversity and Biogeography of Human Oral Saliva Microbial Communities Revealed by the Earth Microbiome Project.

ABSTRACT: The oral cavity is an important window for microbial communication between the environment and the human body. The oral microbiome plays an important role in human health. However, compared to the gut microbiome, the oral microbiome has been poorly explored. Here, we analyzed 404 datasets from human oral saliva samples published by the Earth Microbiome Project (EMP) and compared them with 815 samples from the human gut, nose/pharynx, and skin. The diversity of the human saliva microbiome varied significantly among individuals, and the community compositions were complex and diverse. The saliva microbiome showed the lowest species diversity among the four environment types. Human oral habitats shared a small core bacterial community containing only 14 operational taxonomic units (OTUs) unde

SUBMITTER: Wang J 

PROVIDER: S-EPMC9234457 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature