Biomineralization associated alkaline phosphatase as a potential marker of bone metastasis in the patients with invasive breast cancer.

ABSTRACT: Breast Cancer is the most predominant form of cancer among women worldwide. It has been rigorously studied for biomarker identifications and therapeutic targets. However, various potential genes and their clinical relevance to breast cancer remain unexplored. The heterogeneity of breast cancer is one of the major challenges in early detection. Several studies have reported the significant role of alkaline phosphate (ALP) in the regulation of tumor growth and overall free survival in the pathogenesis of different cancer, including breast cancer which may offer unique therapeutic targets. Therefore, these findings demand a comprehensive study for the biogenesis of ALP genes. This study aims to expression profiling of alkaline phosphate genes in breast cancer and to identify the key pathways

SUBMITTER: Tayubi IA 

PROVIDER: S-EPMC9234708 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature