Oral or Vaginal Misoprostol for Labor Induction and Cesarean Delivery Risk.

ABSTRACT:

Objective

To evaluate whether cervical ripening with oral misoprostol increases cesarean delivery risk and prolongs time to vaginal delivery compared with vaginal misoprostol in a predominantly overweight population.

Methods

This single center, retrospective cohort study was performed at a tertiary care academic medical center and compared labor induction outcomes with vaginal misoprostol to outcomes with oral misoprostol after a complete institutional shift to oral misoprostol. Labor induction using 25 micrograms vaginal misoprostol in 2013-2014 was compared with 50 micrograms oral misoprostol in 2014-2015. The primary outcome was cesarean delivery. Secondary outcomes included time to vaginal delivery, uterine tachysystole, maternal hemorrhage, and composite adverse neonata

SUBMITTER: Handal-Orefice RC 

PROVIDER: S-EPMC9234943 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature