Use of Bayes factors to evaluate the effects of host genetics, litter and cage on the rabbit cecal microbiota.

ABSTRACT:

Background

The rabbit cecum hosts and interacts with a complex microbial ecosystem that contributes to the variation of traits of economic interest. Although the influence of host genetics on microbial diversity and specific microbial taxa has been studied in several species (e.g., humans, pigs, or cattle), it has not been investigated in rabbits. Using a Bayes factor approach, the aim of this study was to dissect the effects of host genetics, litter and cage on 984 microbial traits that are representative of the rabbit microbiota.

Results

Analysis of 16S rDNA sequences of cecal microbiota from 425 rabbits resulted in the relative abundances of 29 genera, 951 operational taxonomic units (OTU), and four microbial alpha-diversity indices. Each of these microbial traits was adj

SUBMITTER: Velasco-Galilea M 

PROVIDER: S-EPMC9235133 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature