Assessing organ at risk position variation and its impact on delivered dose in kidney SABR.

ABSTRACT:

Background

Delivered organs at risk (OARs) dose may vary from planned dose due to interfraction and intrafraction motion during kidney SABR treatment. Cases of bowel stricture requiring surgery post SABR treatment were reported in our institution. This study aims to provide strategies to reduce dose deposited to OARs during SABR treatment and mitigate risk of gastrointestinal toxicity.

Methods

Small bowel (SB), large bowel (LB) and stomach (STO) were delineated on the last cone beam CT (CBCT) acquired before any dose had been delivered (PRE CBCT) and on the first CBCT acquired after any dose had been delivered (MID CBCT). OAR interfraction and intrafraction motion were estimated from the shortest distance between OAR and the internal target volume (ITV). Adaptive radiation t

SUBMITTER: Gaudreault M 

PROVIDER: S-EPMC9235197 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature