T2 mapping and fat quantification of lumbar paraspinal muscle in ankylosing spondylitis: a case control study.

ABSTRACT:

Background

To compare changes in the composition of paraspinal muscles of patients with ankylosing spondylitis (AS) and matched healthy controls using T2 mapping and T2 IDEAL and correlate the quantitative magnetic resonance imaging (qMRI) results with clinical assessments of AS patients.

Method

In total, 37 AS patients and 37 healthy controls were enrolled in the case control study. T2 mapping with and without fat saturation and IDEAL imaging were used to assess the multifidus (MF) and erector spinae (ES) at the levels of L3/L4 and L4/L5 for all subjects. Mean T2_non-fatsat, T2_fat, T2_fatsat, cross-sectional area (CSA), and fat fraction (FF) were compared between AS and healthy controls. Correlations of qMRI results with clinical assessments w

SUBMITTER: Huang R 

PROVIDER: S-EPMC9235229 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature