Consideration of sex and gender differences in addiction medication response.

ABSTRACT: Substance use continues to contribute to significant morbidity and mortality in the United States, for both women and men, more so than another other preventable health condition. To reduce the public health burden attributable to substances, the National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism have identified that medication development for substance use disorder is a high priority research area. Furthermore, both Institutes have stated that research on sex and gender differences in substance use medication development is a critical area. The purpose of the current narrative review is to highlight how sex and gender have been considered (or not) in medication trials for substance use disorders to clarify and summarize what is known regarding sex

SUBMITTER: McKee SA 

PROVIDER: S-EPMC9235243 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature