Outcome of patients with severe alcoholic hepatitis after Model for End-Stage Liver Disease-based allocation system implementation in Korea.

ABSTRACT:

Background

The Model for End-Stage Liver Disease (MELD)-based allocation system was implemented in Korea in July 2016 without a mandatory abstinence period for liver transplantation (LT) listing. However, the impact of the allocation policy has not been evaluated in patients with severe alcoholic hepatitis (AH).

Methods

A total of 81 consecutive patients with severe AH between January 2014 and December 2018 were analyzed. The clinical course of patients before and after the implementation of the MELD-based allocation system was assessed.

Results

More patients received LT (25%-65%) after the MELD allocation system was implemented. The increase in patients receiving deceased donor LT was dramatic (17%-51%, P=0.001) compared to patients receiving living donor LT (7%-14%,

SUBMITTER: Kwon TJ 

PROVIDER: S-EPMC9235328 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature