QuCo: quartet-based co-estimation of species trees and gene trees.

ABSTRACT:

Motivation

Phylogenomics faces a dilemma: on the one hand, most accurate species and gene tree estimation methods are those that co-estimate them; on the other hand, these co-estimation methods do not scale to moderately large numbers of species. The summary-based methods, which first infer gene trees independently and then combine them, are much more scalable but are prone to gene tree estimation error, which is inevitable when inferring trees from limited-length data. Gene tree estimation error is not just random noise and can create biases such as long-branch attraction.

Results

We introduce a scalable likelihood-based approach to co-estimation under the multi-species coalescent model. The method, called quartet co-estimation (QuCo), takes as input independently inferred

SUBMITTER: Rabiee M 

PROVIDER: S-EPMC9235488 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature