Better Prognosis and Survival in Esophageal Cancer Survivors After Comorbid Second Primary Malignancies: A SEER Database-Based Study.

ABSTRACT:

Background

With the development of surgical techniques and advances in systemic treatments, the survival time of esophageal cancer survivors has increased; however, the chance of developing a second primary malignancy (SPM) has also increased. These patients' prognosis and treatment plans remain inconclusive.

Objectives

We aimed to evaluate and predict the survival of patients with esophageal cancer with second primary tumors, to provide insights and the latest data on whether to pursue more aggressive treatment.

Materials and methods

We selected esophageal cancer cases from the latest available data from the SEER database on April 15, 2021. We performed life table analysis, Kaplan-Meier analysis, and univariate and multivariate Cox proportional hazards analysis to as

SUBMITTER: Ye J 

PROVIDER: S-EPMC9235858 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature