Salmonella enterica subsp. II serovar 4,5,12:a:- may cause gastroenteritis infections in humans.

ABSTRACT: Some serovars of Salmonella are not or rare found to cause salmonellosis in human. In our clinic-based surveillance, three rare Salmonella 4,5,12:a:- strains were recovered from three patients with diarrhea. To explore their genetic and epidemiological characteristics and pathogenesis, we conducted whole-genome sequencing, in vitro invasion assays in mammalian cells, and in vivo virulence assays in an animal model. The three isolates had indistinguishable molecular patterns and similar genome sequences, and clustered together with an isolate from edible fish traded among countries. The isolates had biochemical reactions identical with those of Salmonella subspecies enterica but belonged to subspecies salamae according to genome phylogeny, re

SUBMITTER: Yan M 

PROVIDER: S-EPMC9235882 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature