A comparative study on silicon nitride, titanium and polyether ether ketone on mouse pre-osteoblast cells.

ABSTRACT: The current study provides more insights about the surface bioactivity of the silicon nitride (Si₃N₄) as a potential candidate for bone regeneration in craniofacial and orthopaedic applications compared with conventional implantation materials. Current skeletal reconstructive materials such as titanium and polyether ether ketone (PEEK) are limited by poor long-term stability, biocompatibility and prolonged healing. Si₃N₄ is an FDA-approved material for an intervertebral spacer in spinal fusion applications. It is biocompatible and has antimicrobial properties. Here, we hypothesize that Si₃N₄ was found to be an osteoconductive material and conducts the growth, differentiation of MC3T3-E1 cells for extracellular matrix deposit

SUBMITTER: Ahuja N 

PROVIDER: S-EPMC9236125 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature