Analytic consistency and neural correlates of peak alpha frequency in the study of pain.

ABSTRACT:

Background

Several studies have found evidence of reduced resting-state peak alpha frequency (PAF) in populations with pain. However, the stability of PAF from different analytic pipelines used to study pain has not been determined and underlying neural correlates of PAF have not been validated in humans.

New method

For the first time we compare analytic pipelines and the relationship of PAF to activity in the whole brain and thalamus, a hypothesized generator of PAF. We collected resting-state functional magnetic resonance imaging (rs-fMRI) data and subsequently 64 channel resting-state electroencephalographic (EEG) from 47 healthy men, controls from an ongoing study of chronic prostatitis (a pain condition affecting men). We identified important variations in EEG processin

SUBMITTER: McLain NJ 

PROVIDER: S-EPMC9236562 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature