Effects of root-end filling materials on vascular endothelial cell proliferation and tube formation

ABSTRACT:

Background/purpose

Regarding root-end filling materials in apical surgery, sealing ability and biocompatibility are useful for treatment. Angiogenesis, which occurs in the process of periapical wound healing, is closely related to bone formation. In this study, we investigated the effects of root-end filling materials on vascular endothelial cell proliferation and angiogenesis.

Materials and methods

Mineral trioxide aggregate (MTA), 4-methacryloxyethyl trimellitate anhydride/methyl methacrylate-tri-n-butyl borane (4-META/MMA-TBB) resin, Super EBA, and CS-BG-multi, bioactive glass-related materials, were used. After curing, each material was soaked in a medium for 1 or 7 days, and then cultured for 1–7 days to investigate the effects on human umbilical vein endothelial cel

SUBMITTER: Matsuzaki E 

PROVIDER: S-EPMC9236890 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature