Clinical Characteristics and Treatment Response in Microscopic Colitis Based on Age at Diagnosis: A Multicenter Retrospective Study.

ABSTRACT:

Background

Microscopic colitis (MC) primarily affects older adults; thus, data in younger patients are scarce.

Aims

To compare clinical characteristics and treatment response by age at diagnosis.

Methods

This retrospective cohort study was performed at Mayo Clinic and Massachusetts General Hospital. Patients were chosen consecutively using established databases. Patients were 'younger' if age at diagnosis was ≤ 50 years and 'older' if age > 50 years. Treatment outcomes were captured for induction (12 ± 4 weeks), based on the total number of daily stools, and defined as remission (complete resolution), response (≥ 50% improvement), non-response (< 50% improvement), and intolerance. Patients were considered 'responders' if they had remission or response and 'non-respond

SUBMITTER: Kamboj AK 

PROVIDER: S-EPMC9236988 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature