The Role of Egg Yolk in Modulating the Virulence of Salmonella Enterica Serovar Enteritidis.

ABSTRACT: Contribution of food vehicles to pathogenicity of disease-causing microorganisms is an important but overlooked research field. The current study was initiated to reveal the relationship between virulence of Salmonella enterica serovar Enteritidis and egg yolk as a hosting medium. Mice were orally challenged with Salmonella Enteritidis cultured in egg yolk or tryptic soy broth (TSB). Additionally, mice were challenged with Salmonella Enteritidis cultured in TSB, followed by administration of sterile egg yolk, to discern the difference between pre-growth of the pathogen and its mere presence in egg yolk during infection. The pathogen's Lethal dose 50 (LD₅₀) was the lowest when grown in yolk (2.8×10² CFU), compared to 1.1×10³ CFU in TSB,

SUBMITTER: Xu Y 

PROVIDER: S-EPMC9237210 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature