Maternal Thyroid Function and Birth Weight in Twins.

ABSTRACT:

Context

Thyroid hormones are associated with birth weight in singleton pregnancy. Twin pregnancies need more thyroid hormones to maintain the normal growth and development of the fetuses compared with single pregnancy.

Objective

We aimed to investigate the association of thyroid hormones and birth weight in twins.

Methods

This was a retrospective cohort study in a Chinese population. Pregnant women who received regular antenatal health care and delivered live-born twins from 2014 to 2019 were included (n = 1626). Linear mixed model with restricted cubic splines and logistic regression models were used to estimate the association of thyroid hormones with birth weight and birth weight discordance in twins.

Results

We observed that both thyrotropin (TSH) and free

SUBMITTER: Liu XS 

PROVIDER: S-EPMC9237444 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature