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Clinical utility of antifungal susceptibility testing.


ABSTRACT: Invasive fungal diseases cause significant morbidity and mortality, in particular affecting immunocompromised patients. Resistant organisms are of increasing importance, yet there are many notable differences in the ability to both perform and interpret antifungal susceptibility testing compared with bacteria. In this review, we will highlight the strengths and limitations of resistance data of pathogenic yeasts and moulds that may be used to guide treatment and predict clinical outcomes.

SUBMITTER: McCarty TP 

PROVIDER: S-EPMC9237445 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Clinical utility of antifungal susceptibility testing.

McCarty Todd P TP   Luethy Paul M PM   Baddley John W JW   Pappas Peter G PG  

JAC-antimicrobial resistance 20220628 3


Invasive fungal diseases cause significant morbidity and mortality, in particular affecting immunocompromised patients. Resistant organisms are of increasing importance, yet there are many notable differences in the ability to both perform and interpret antifungal susceptibility testing compared with bacteria. In this review, we will highlight the strengths and limitations of resistance data of pathogenic yeasts and moulds that may be used to guide treatment and predict clinical outcomes. ...[more]

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