Association of SARS-CoV-2 Seropositivity and Symptomatic Reinfection in Children in Nicaragua.

ABSTRACT:

Importance

The impact of the SARS-CoV-2 pandemic on children remains unclear. Better understanding of the burden of COVID-19 among children and their risk of reinfection is crucial, as they will be among the last groups vaccinated.

Objective

To characterize the burden of COVID-19 and assess how risk of symptomatic reinfection may vary by age among children.

Design, setting, and participants

In this prospective, community-based pediatric cohort study conducted from March 1, 2020, to October 15, 2021, 1964 nonimmunocompromised children aged 0 to 14 years were enrolled by random selection from the Nicaraguan Pediatric Influenza Cohort, a community-based cohort in District 2 of Managua, Nicaragua. Additional newborn infants aged 4 weeks or younger were randomly selected a

SUBMITTER: Kubale J 

PROVIDER: S-EPMC9237791 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature