Gold nanomaterials for oral cancer diagnosis and therapy: Advances, challenges, and prospects.

ABSTRACT: Early diagnosis and treatment of oral cancer are vital for patient survival. Since the oral cavity accommodates the second largest and most diverse microbiome community after the gut, the diagnostic and therapeutic approaches with low invasiveness and minimal damage to surrounding tissues are keys to preventing clinical intervention-related infections. Gold nanoparticles (AuNPs) are widely used in the research of cancer diagnosis and therapy due to their excellent properties such as surface-enhanced Raman spectroscopy, surface plasma resonance, controlled synthesis, the plasticity of surface morphology, biological safety, and stability. AuNPs had been used in oral cancer detection reagents, tumor-targeted therapy, photothermal therapy, photodynamic therapy, and other combination therapies

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC9237953 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature