Non-invasive diagnosis strategy of hepatocellular carcinoma in low-risk population.

ABSTRACT:

Aims

With prevalence of hepatocellular carcinoma (HCC) in low-risk population (LRP), establishing a non-invasive diagnostic strategy becomes increasingly urgent to spare unnecessary biopsies in this population. The purposes of this study were to find characterisics of HCC and to establish a proper non-invasive method to diagnose HCC in LRP.

Methods

A total of 681 patients in LRP (defined as the population without cirrhosis, chronic HBV infection or HCC history) were collected from 2 institutions. The images of computed tomography (CT) and magnetic resonance imaging (MRI) were manually analysed. We divided the patients into the training cohort (n = 324) and the internal validating cohort (n = 139) by admission time in the first institution. The cohort in the second institutio

SUBMITTER: Xie Z 

PROVIDER: S-EPMC9238050 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature