Monkeypox: An extra burden on global health.
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ABSTRACT:
SUBMITTER: Saied AA
PROVIDER: S-EPMC9238059 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Publications
Monkeypox: An extra burden on global health.
Saied AbdulRahman A AA Priyanka Metwally Asmaa A AA Choudhary Om Prakash OP
International journal of surgery (London, England) 20220628
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Project description:In 2003, the United States saw an epidemic of monkeypox that was later traced back to rodents of West Africa infected with the monkeypox virus (MPXV). Disease in the United States seemed less severe than the smallpox-like disease in the Democratic Republic of the Congo (DRC). In this study, researchers analyzed data from Central Africa: two distinct MPXV clades were confirmed by sequencing the genomes of MPXV isolates from Western Africa, the United States, and Central Africa. By comparing open reading frames across MPXV clades, scientists can infer which virus proteins might account for the observed variation in pathogenicity in humans. Monkeypox can be prevented and controlled with a better understanding of MPXV's molecular etiology and epidemiological and clinical features. In light of the current outbreaks worldwide, we provide updated information on monkeypox for medical professionals in this review.
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