Health Care Resource Utilization for Esophageal Cancer Using Proton versus Photon Radiation Therapy.

ABSTRACT:

Purpose

In patients treated with chemoradiation for esophageal cancer (EC), randomized trial data demonstrate that proton beam therapy (PBT) reduces toxicities and postoperative complications (POCs) compared with intensity-modulated radiation therapy (IMRT). However, whether radiation therapy modality affects postoperative health care resource utilization remains unknown.

Materials and methods

We examined 287 patients with EC who received chemoradiation (prescribed 50.4 Gy/GyE) followed by esophagectomy, including a real-world observational cohort of 237 consecutive patients treated from 2007 to 2013 with PBT (n = 81) versus IMRT (n = 156); and an independent, contemporary comparison cohort of 50 patients from a randomized trial treated from 2012 to 2019 with PBT (n = 21) ve

SUBMITTER: Lin SH 

PROVIDER: S-EPMC9238132 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature