Prediction of Prophages and Their Host Ranges in Pathogenic and Commensal Neisseria Species.

ABSTRACT: The genus Neisseria includes two pathogenic species, N. gonorrhoeae and N. meningitidis, and numerous commensal species. Neisseria species frequently exchange DNA with one another, primarily via transformation and homologous recombination and via multiple types of mobile genetic elements (MGEs). Few Neisseria bacteriophages (phages) have been identified, and their impact on bacterial physiology is poorly understood. Furthermore, little is known about the range of species that Neisseria phages can infect. In this study, we used three virus prediction tools to scan 248 genomes of 21 different Neisseria species and identified 1,302 unique predicted prophages. Using comparative genomics, we found that many predictions are dissimilar from prophages and other M

SUBMITTER: Orazi G 

PROVIDER: S-EPMC9238386 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature