Bidirectional Association Between Kidney Function and Atrial Fibrillation: A Population-Based Cohort Study.

ABSTRACT: Background Consensus lacks concerning a bidirectional association between kidney function and atrial fibrillation (AF), but this is crucial information for prevention/treatment efforts for both chronic kidney disease and AF. Therefore, we investigated the bidirectional association between kidney function and AF. Methods and Results This study was a prospective cohort study including 9228 participants (mean age, 64.9 years; 57.2% women) with information on kidney function (estimated glomerular filtration rate [eGFR] based on serum creatinine [eGFRcreat], cystatin C [eGFRcys], or both [eGFRcreat-cys], and urine albumin-to-creatinine ratio) and AF. Reduced kidney function was defined as eGFRcreat <60 mL/min per 1.73 m². Cox proportional-hazards, logistic regression, linear mixed, a

SUBMITTER: van der Burgh AC 

PROVIDER: S-EPMC9238570 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature