Phyletic Distribution and Diversification of the Phage Shock Protein Stress Response System in Bacteria and Archaea.

ABSTRACT: Maintaining cell envelope integrity is of vital importance for all microorganisms. Not surprisingly, evolution has shaped conserved protein protection networks that connect stress perception, transmembrane signal transduction, and mediation of cellular responses upon cell envelope stress. The phage shock protein (Psp) stress response is one such conserved protection network. Most knowledge about the Psp response derives from studies in the Gram-negative model bacterium Escherichia coli, where the Psp system consists of several well-defined protein components. Homologous systems were identified in representatives of the Proteobacteria, Actinobacteria, and Firmicutes. However, the Psp system distribution in the microbial world remains largely unknown. By carrying out a l

SUBMITTER: Popp PF 

PROVIDER: S-EPMC9239133 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature