Association of Growth Trajectory Profiles with Asthma Development in Infants Hospitalized with Bronchiolitis.

ABSTRACT:

Background

Little is known about the relationship of longitudinal growth trajectory in early life with asthma development, particularly in infants with bronchiolitis (a high-risk population).

Objective

Among infants with bronchiolitis, we aimed to identify growth trajectory profiles and determine their longitudinal relationship with the risk for developing childhood asthma.

Methods

A multicenter prospective study enrolled infants (aged <1 year) hospitalized for bronchiolitis. We identified growth trajectory profiles-derived from body mass index-for-age at ages 0, 6, 12, 15, 18, 24, and 36 months by using a longitudinal clustering method. We examined associations between growth trajectory profiles and asthma development by age 5 years.

Results

The analytic cohor

SUBMITTER: Nanishi M 

PROVIDER: S-EPMC9239901 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature