Ontology highlight
ABSTRACT:
SUBMITTER: Rosa Duque JS
PROVIDER: S-EPMC9240007 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Rosa Duque Jaime S JS Wang Xiwei X Leung Daniel D Cheng Samuel M S SMS Cohen Carolyn A CA Mu Xiaofeng X Hachim Asmaa A Zhang Yanmei Y Chan Sau Man SM Chaothai Sara S Kwan Kelvin K H KKH Chan Karl C K KCK Li John K C JKC Luk Leo L H LLH Tsang Leo C H LCH Wong Wilfred H S WHS Cheang Cheuk Hei CH Hung Timothy K TK Lam Jennifer H Y JHY Chua Gilbert T GT Tso Winnie W Y WWY Ip Patrick P Mori Masashi M Kavian Niloufar N Leung Wing Hang WH Valkenburg Sophie S Peiris Malik M Tu Wenwei W Lau Yu Lung YL
Nature communications 20220628 1
We present an interim analysis of a registered clinical study (NCT04800133) to establish immunobridging with various antibody and cellular immunity markers and to compare the immunogenicity and reactogenicity of 2-dose BNT162b2 and CoronaVac in healthy adolescents as primary objectives. One-dose BNT162b2, recommended in some localities for risk reduction of myocarditis, is also assessed. Antibodies and T cell immune responses are non-inferior or similar in adolescents receiving 2 doses of BNT162 ...[more]