The Gut Mycobiome Characterization of Gestational Diabetes Mellitus and Its Association With Dietary Intervention.

ABSTRACT: Gestational diabetes mellitus (GDM) is a high-risk pregnancy complication that is associated with metabolic disorder phenotypes, such as abnormal blood glucose and obesity. The active interface between gut microbiota and diet contributes to metabolic homeostasis in GDM. However, the contributions of gut mycobiome have been neglected. Here, we profiled the gut fungi between GDM and healthy subjects at two time points and investigate whether variations in gut mycobiome correlate with key features of host metabolism and diet management in this observational study. We identified that Hanseniaspora, Torulaspora, Auricularia, Alternaria, and Candida contributed to GDM patient clustering, indicating that these fungal taxa are associated with abnormal blood glucose levels, and the ca

SUBMITTER: Wu N 

PROVIDER: S-EPMC9240440 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature