Ultrasonication for production of nanoliposomes with encapsulated soy protein concentrate hydrolysate: Process optimization, vesicle characteristics and in vitro digestion

ABSTRACT: Graphical abstract Highlights • Soy protein concentrate hydrolysate (SPH) has been utilized as a mixture of antioxidant peptides.• Novel ultrasonicated hydrolysate-loaded nanoliposome carriers are developed.• Encapsulated SPH influenced positively the liposomal nanocarriers' stability.• Tailored release properties of SPH are shown by in vitro gastrointestinal digestion study.• Unilamelarity and sphericity of nanoliposomes have been confirmed by TEM and SEM. This study presents the state-of-art research about the assembly of soy proteins in nanocarriers, liposomes, and its design includes different physicochemical strategies and approaches: two-step enzymatic hydrolysis of soy concentrate, hydrolysate encapsulation by using phospholipids and cholesterol, and application of ultrasonication.

SUBMITTER: Pavlovic N 

PROVIDER: S-EPMC9240801 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature