Multi-centre classification of functional neurological disorders based on resting-state functional connectivity.

ABSTRACT:

Background

Patients suffering from functional neurological disorder (FND) experience disabling neurological symptoms not caused by an underlying classical neurological disease (such as stroke or multiple sclerosis). The diagnosis is made based on reliable positive clinical signs, but clinicians often require additional time- and cost consuming medical tests and examinations. Resting-state functional connectivity (RS FC) showed its potential as an imaging-based adjunctive biomarker to help distinguish patients from healthy controls and could represent a "rule-in" procedure to assist in the diagnostic process. However, the use of RS FC depends on its applicability in a multi-centre setting, which is particularly susceptible to inter-scanner variability. The aim of this study was to t

SUBMITTER: Weber S 

PROVIDER: S-EPMC9240866 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature