Feasibility study of a randomised controlled trial of preoperative and postoperative nutritional supplementation in major lung surgery.

ABSTRACT:

Objectives

Malnutrition and weight loss are important risk factors for complications after lung surgery. However, it is uncertain whether modifying or optimising perioperative nutritional state with oral supplements results in a reduction in malnutrition, complications or quality of life.

Design

A randomised, open label, controlled feasibility study was conducted to assess the feasibility of carrying out a large multicentre randomised trial of nutritional intervention. The intervention involved preoperative carbohydrate-loading drinks (4×200 mL evening before surgery and 2×200 mL the morning of surgery) and early postoperative nutritional protein supplement drinks two times per day for 14 days compared with the control group receiving an equivalent volume of water.

Settin

SUBMITTER: Kerr A 

PROVIDER: S-EPMC9240939 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature