Du13 encodes a C₂ H₂ zinc-finger protein that regulates Wx^b pre-mRNA splicing and microRNA biogenesis in rice endosperm.

ABSTRACT: Amylose content is a crucial physicochemical property responsible for the eating and cooking quality of rice (Oryza sativa L.) grain and is mainly controlled by the Waxy (Wx) gene. Previous studies have identified several Dull genes that modulate the expression of the Wx^b allele in japonica rice by affecting the splicing efficiency of the Wx^b pre-mRNA. Here, we uncover dual roles for a novel Dull gene in pre-mRNA splicing and microRNA processing. We isolated the dull mutant, du13, with a dull endosperm and low amylose content. Map-based cloning showed that Du13 encodes a C₂ H₂ zinc-finger protein. Du13 coordinates with the nuclear cap-binding complex to regulate the splicing of Wx^b transcripts in rice endosperm. Moreover, Du13 also reg

SUBMITTER: Cai Y 

PROVIDER: S-EPMC9241381 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature