The Lumenal Microbiota Varies Biogeographically in the Gastrointestinal Tract of Rhesus Macaques.

ABSTRACT: The strategy of adjusting the composition of gastrointestinal microbiota has shown great promise for the treatment of diseases. Currently, the relationship between gut microbes and human diseases is mainly presented by the fecal microbiota from the colon. Due to the limits of sampling, the healthy baseline of biogeographic microbiota in the human gastrointestinal tract remains blurry. Captive nonhuman primates (NHPs) present a "humanized" intestinal microbiome and may make up for the lack of atlas data for better understanding of the gut microbial composition and diseases. Therefore, the intestinal microbiota of 6 GIT regions of healthy rhesus monkeys were analyzed in this study; our results showed that Proteobacteria gradually decreased from the small intestine to the large intesti

SUBMITTER: Yan Y 

PROVIDER: S-EPMC9241614 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature