Screening for subclinical rheumatic heart disease: addressing borderline disease in a real-world setting.

ABSTRACT:

Aims

The World Heart Federation (WHF) criteria identify a large borderline rheumatic heart disease (RHD) category that has hampered the implementation of population-based screening. Inter-scallop separations (ISS) of the posterior mitral valve leaflet, a recently described normal variant of the mitral valve, appears to be an important cause of mild mitral regurgitation (MR) leading to misclassification of cases as WHF 'borderline RHD'. This study aims to report the findings of the Echo in Africa project, a large-scale RHD screening project in South Africa and determine what proportion of borderline cases would be re-classified as normal if there were a systematic identification of ISS-related MR.

Methods and results

A prospective cross-sectional study of underserved secondar

SUBMITTER: Hunter LD 

PROVIDER: S-EPMC9242066 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature