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Ketorolac and Predicted Severe Acute Pancreatitis: A Randomized, Controlled Clinical Trial.


ABSTRACT: Objective: We evaluated the effect of ketorolac on reducing the severity of acute pancreatitis.Design and Setting: Randomized clinical trial performed in a University hospital.Participants: There were 56 adult patients, with predicted severe acute pancreatitis, randomly divided into two groups.Methods: The patients in the study group received intravenous ketorolac, 10 mg, three times daily from the time of enrollment for a maximum of 5 days, as needed, along with standard medical treatment. Primary outcome measure was the change in the serum level of high sensitive C-reactive protein (hs-CRP). Patients were also followed up in terms of hospitalization duration, need for intensive care unit (ICU), organ failure development, persistent organ failure, pancreatic ne

SUBMITTER: Shariatpanahi ZV 

PROVIDER: S-EPMC9242735 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature