Performance of the aldosterone-to-renin ratio as a screening test for primary aldosteronism in primary care.

ABSTRACT: Primary aldosteronism (PA) is the most common and potentially curable form of secondary hypertension, affecting 5-10% of primary care patients with hypertension. Primary care physicians have an important role in initiating the screening for PA in patients with hypertension and referring to a specialist service depending on the screening test results. The currently recommended screening test for PA is the plasma aldosterone-to-renin ratio (ARR). Test results are influenced by medications so careful patient preparation is required including adjusting existing antihypertensive medications to avoid diagnostic errors. A range of laboratory method-dependent ARR thresholds are used for the screening of PA around the world. Periodic clinical audits and case reviews by clinicians and the laboratory

SUBMITTER: Ariens J 

PROVIDER: S-EPMC9242901 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature