Self-reported Race, Serum Creatinine, Cystatin C, and GFR in Children and Young Adults With Pediatric Kidney Diseases: A Report From the Chronic Kidney Disease in Children (CKiD) Study.

ABSTRACT:

Rationale & objective

Recent reassessment of the use of race in estimated glomerular filtration rate (eGFR) in adults has instigated questions about the role of race in eGFR expressions for children. Little research has examined the associations of self-reported race with measured GFR (mGFR) adjusting for serum creatinine or cystatin C in children and young adults with chronic kidney disease (CKD). This study examined these associations and evaluated the performance of the previously published "U25" (under the age of 25 years) eGFR equations in a large cohort of children and young adults with CKD.

Study design

Observational cohort study.

Setting & participants

Participants in the Chronic Kidney Disease in Children (CKiD) study including 190 Black and 675 non-Black par

SUBMITTER: Ng DK 

PROVIDER: S-EPMC9243196 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature