First genome-wide association study of 99 body measures derived from 3-dimensional body scans.

ABSTRACT: Body height, body mass index, hip and waist circumference are important risk factors or outcome variables in clinical and epidemiological research with complex underlying genetics. However, these classical anthropometric traits represent only a very limited view on the human body and other traits with potentially higher functional specificity are not yet studied to a larger extent. Participants of LIFE-Adult were assessed by three-dimensional body scanner VITUS XXL determining 99 high-quality anthropometric traits in parallel. Genotyping was performed by Axiom Genome-Wide CEU 1 Array Plate microarray technology and imputation was done using 1000 Genomes phase 3 reference panel. Combined phenotype and genetic information are available for a total of 7,562 participants. Largest heritabilitie

SUBMITTER: Kuhnapfel A 

PROVIDER: S-EPMC9243350 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature