Risk Factors for Neck Nodal Metastasis in Papillary Thyroid Cancer With BRAF V600E Mutation.

ABSTRACT:

Background

The BRAF V600E mutation is the most common genetic variant in papillary thyroid cancer (PTC), but the relationship between the BRAF V600E mutation in PTC and cervical lymph node metastasis (LNM) remains controversial.

Objective

To estimate risk factors for neck nodal metastasis in PTC with BRAF V600E mutation.

Patients

A total of 292 patients diagnosed with BRAF V600E mutation related PTC were admitted.

Design

In this retrospective study, data from 292 patients, including clinical, molecular, and ultrasonic characteristics, were analyzed. Univariate and multivariate logistic regression analyses were applied to identify risk factors for LNM in PTC with the BRAF V600E mutation.

Results

In the univariate analysis of all PTC patients with t

SUBMITTER: Han Y 

PROVIDER: S-EPMC9243356 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature