A Novel Approach to Estimating the Cortical Sources of Sleep Spindles Using Simultaneous EEG/MEG.

ABSTRACT: Sleep spindles, defining oscillations of stage II non-rapid eye movement sleep (N2), mediate sleep-dependent memory consolidation. Spindles are disrupted in several neurodevelopmental, neuropsychiatric, and neurodegenerative disorders characterized by cognitive impairment. Increasing spindles can improve memory suggesting spindles as a promising physiological target for the development of cognitive enhancing therapies. This effort would benefit from more comprehensive and spatially precise methods to characterize spindles. Spindles, as detected with electroencephalography (EEG), are often widespread across electrodes. Available evidence, however, suggests that they act locally to enhance cortical plasticity in the service of memory consolidation. Here, we present a novel method to enhance

SUBMITTER: Mylonas D 

PROVIDER: S-EPMC9243385 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature