Pre-pregnancy obesity and the risk of peripartum cardiomyopathy: A systematic review and meta-analysis.

ABSTRACT: The outcome of this review is to assess the association between pre-pregnancy obesity and PPCM incidence. There were a total of 5.373.581 participants were included in this study. Pre-pregnancy obesity was significantly associated with PPCM incidence compared to normal-weight subjects (OR = 1.79 (1.16,2.76); p = 0.008; I² = 59%, P_{heterogeneity} = 0.04). The sub-group analysis showed that pre-pregnancy women with obesity class I (OR = 1.58 (1.20,2.07); p = 0.001; I² = 0%, P_{heterogeneity} = 0.64) and class II and III (OR = 2.65 (2.04,3.45); p < 0.001; I² = 6%, P_{heterogeneity} = 0.36) was significantly associated with PPCM incidence compared to normal-weight subjects.

SUBMITTER: Putra ICS 

PROVIDER: S-EPMC9243620 | biostudies-literature | 2022 May-Jun

REPOSITORIES: biostudies-literature