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Intravenous iron supplementation treats anemia and reduces blood transfusion requirements in patients undergoing coronary artery bypass grafting-A prospective randomized trial.


ABSTRACT:

Study objective

Preoperative anemia results in two- to sixfold increased incidence of perioperative blood transfusion requirements and reduced postoperative hemoglobin (Hb) level. This prospective study was designed to investigate the effect of preoperative intravenous infusion of iron on Hb levels, blood transfusion requirements, and incidence of postoperative adverse events in patients undergoing coronary artery bypass grafting.

Design

Prospective randomized trial.

Setting

Academic university hospital.

Patients

Eighty patients (52-67 years old) underwent coronary artery bypass grafting and received either iron therapy or saline infusion preoperatively.

Interventions

Patients were randomly allocated to iron or placebo groups. In the iron group, patients

SUBMITTER: Shokri H 

PROVIDER: S-EPMC9244267 | biostudies-literature | 2022 Apr-Jun

REPOSITORIES: biostudies-literature