First pass effect vs multiple passes complete reperfusion: A retrospective study.

ABSTRACT:

Background and purpose

First pass effect (FPE) is defined as achieving modified treatment in cerebral infarction (mTICI) grade 2c/3 reperfusion from the first pass and is associated with more favorable outcomes. We aimed to compare FPE and non-FPE using a large database and further compare first-pass mTICI 2b with multiple passes mTICI 3.

Methods

A retrospective cohort study of acute ischemic stroke patients who received mechanical thrombectomy at a high-volume center was performed. Baseline characteristics and outcomes including rates of discharge and 90-day functional independence (modified Rankin Scale ≤2), mortality, symptomatic, and asymptomatic intracerebral hemorrhage were compared.

Results

Of the 637 patients included, 294 achieved FPE; 161 patients had multip

SUBMITTER: Hassan AE 

PROVIDER: S-EPMC9244755 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature