Scoring Assessments in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

ABSTRACT: Epidermal necrolysis, the unifying term for Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), is a severe cutaneous drug reaction associated with high morbidity and mortality. Given the rarity of this disease, large-scale prospective research studies are limited. Significant institutional and geographical variations in treatment practices highlight the need for standardization of clinical assessment scores and prioritization of research outcome measures in epidermal necrolysis. At the present, clinical assessment is typically simplified to total body surface area (BSA) involvement, with little focus on morphology. Validated clinical scoring systems are used as mortality prognostication tools, with SCORTEN being the best-validated tool thus far, although the ABCD-10 has a

SUBMITTER: Dobry AS 

PROVIDER: S-EPMC9245022 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature