Characterization of Aspergillus terreus Accessory Conidia and Their Interactions With Murine Macrophages.

ABSTRACT: All Aspergillus species form phialidic conidia (PC) when the mycelium is in contact with the air. These small, asexual spores are ideally suited for an airborne dissemination in the environment. Aspergillus terreus and a few closely related species from section Terrei can additionally generate accessory conidia (AC) that directly emerge from the hyphal surface. In this study, we have identified galactomannan as a major surface antigen on AC that is largely absent from the surface of PC. Galactomannan is homogeneously distributed over the entire surface of AC and even detectable on nascent AC present on the hyphal surface. In contrast, β-glucans are only accessible in distinct structures that occur after separation of the conidia from the hyphal surface. During germinat

SUBMITTER: Henß I 

PROVIDER: S-EPMC9245049 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature